PD151746 3-(5-fluoro-1H-indol-3-yl)-2-mercapto-2-Propenoic acid
PD 151746
CAS: 179461-52-0
Molecular Formula: C11H8FNO2S
PD151746 3-(5-fluoro-1H-indol-3-yl)-2-mercapto-2-Propenoic acid - Names and Identifiers
PD151746 3-(5-fluoro-1H-indol-3-yl)-2-mercapto-2-Propenoic acid - Physico-chemical Properties
| Molecular Formula | C11H8FNO2S |
| Molar Mass | 237.25 |
| Solubility | DMSO: ≥ 37 mg/mL |
| Appearance | powder |
| Color | light orange to dark orange |
| Storage Condition | -20°C |
| In vitro study | In SY5Y cells, PD151746 effectively attenuated maitotoxin-induced SLLVY-AMC hydrolysis. In HMEC-1 cells, PD 151746 attenuated oxidized low density lipoprotein (oxLDL)-induced cytotoxicity. |
PD151746 3-(5-fluoro-1H-indol-3-yl)-2-mercapto-2-Propenoic acid - Risk and Safety
| Safety Description | 24/25 - Avoid contact with skin and eyes. |
| UN IDs | 3077 |
| WGK Germany | 3 |
| HS Code | 29339900 |
PD151746 3-(5-fluoro-1H-indol-3-yl)-2-mercapto-2-Propenoic acid - Preparation solution concentration reference
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 4.215 ml | 21.075 ml | 42.15 ml |
| 5 mM | 0.843 ml | 4.215 ml | 8.43 ml |
| 10 mM | 0.421 ml | 2.107 ml | 4.215 ml |
| 5 mM | 0.084 ml | 0.421 ml | 0.843 ml |
Last Update：2024-01-02 23:10:35
PD151746 3-(5-fluoro-1H-indol-3-yl)-2-mercapto-2-Propenoic acid - Reference Information
| Biological activity | PD 151746 is a selective, cell-permeable calpain inhibitor. The Ki for μ-Calpain is 2.6M, which is about 20 times higher than m-Calpain selectivity. |
| in vitro study | in SY5Y cells, PD151746 effectively weaken the SLLVY-AMC hydrolysis induced by maitotoxin. In HMEC-1 cells, PD 151746 attenuates oxidized low density lipoprotein (oxLDL)-induced cytotoxicity. |
Last Update：2024-04-09 21:32:00
Supplier List
Product Name: PD 151746 Visit Supplier Webpage Request for quotation
CAS: 179461-52-0
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
CAS: 179461-52-0
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
Product Name: PD 151746 Visit Supplier Webpage Request for quotation
CAS: 179461-52-0
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
CAS: 179461-52-0
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
View History